1. Do all the preparatory work before starting the folding machine, such as rough checking whether the main parts and screws are loose, whether the rules are moving, whether there are oil stains in the passage, and adding lubricating oil;
2. When starting up, first turn on the motor, so that the machine will idle first (or start the clutch, turn on the front and rear of the paper feeder and the folding machine), after the air pump is turned on, the paper will enter the folding machine part of the folding page. ;
3, when starting the machine, you must first send a signal, check the operation of the car, and then send a signal to hang the long car after the error, and gradually turn to the normal speed;
4. When the machine is in normal operation, it should be checked at any time. In case of failure, it should be analyzed in time, and the parking should be eliminated. It is forbidden to start or eliminate all parts. After the elimination, the signal must be sent first and then turned on;
5. During the operation of the machine, the operator must stick to the job, concentrate on the operation of the machine, and ensure that the folding machine is smoothly folded;
6. When the folding machine is in normal operation, the single shift (8 to 12 hours) is once every two weeks; 2 or 3 shifts (16 to 24 hours) are wiped once a week. The machine should be cleaned and the air path should be smooth to ensure that the production can be started normally after the inspection.
Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (CGMP) - specific phosphodiesterase 5 (PDE5) and an oral drug for the treatment of ED. The physiological mechanism of normal penile erection involves the release of nitric oxide (no) during sexual stimulation. Nitric oxide activates guanylate cyclase in the smooth muscle cells of the corpus cavernosum, which leads to the increase of cGMP level, resulting in the relaxation of the smooth muscle in the corpus cavernosum, the expansion of the cavernous sinus and the inflow of blood. Erectile dysfunction is mainly due to the dysfunction of smooth muscle relaxation of corpus cavernosum. Sildenafil has no direct relaxation effect on human sponges in vitro, but can enhance the effect of nitric oxide by inhibiting the decomposition of cGMP by PDE5 in sponges. Sildenafil can inhibit PDE5, increase cGMP level, relax smooth muscle of corpus cavernosum and let blood flow into corpus cavernosum. Studies have shown that erectile response increases with the increase of dose and plasma concentration, and the efficacy can last for 4 hours (but is weaker than that at 2 hours).
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