The hard capsule is prepared by preparing a certain amount of the drug plus the auxiliary material into a uniform powder or granule, filling the hollow capsule, or directly dispensing the medicine into the empty capsule.
The production process of empty capsules is divided into six processes: sol, silicone, drying, stripping, cutting and nesting, and can also be completed by automated production lines. The operating environment has a temperature of 10 to 25 ° C and a relative humidity of 35% to 45%.
When the drug is filled and mass-produced, an automatic filling machine can be used. According to the movement mode of the main working plate, the automatic capsule filling machine can be divided into two types: intermittent rotation and continuous rotation. Although the intermittent rotary phase continuous rotary type differs in the action of the actuator, the process for producing the hard capsule is almost the same. Taking the intermittent rotary automatic capsule filling machine as an example, the structure and working principle of the hard capsule filling machine are introduced.
During operation, the disordered empty capsules dropped from the storage tank are sorted and oriented, and are arranged in a state in which the capsule cap is in the upper state, and fall into the capsule hole on the main working disc one by one. In the capsular area, the capsular device uses vacuum suction to cause the capsule to fall into the hole of the lower capsule, while the capsule cap remains in the upper capsular plate. In the body dislocation area, the upper capsule is removed together with the capsule cap and the upper opening of the capsule is placed below the dosing device. In the filling zone, the metering device fills the drug into the capsule body. In the abandonment zone, the rejecting device removes the unopened empty capsules from the upper capsule hole. In the closed area of ​​the capsule, the axes of the upper and lower capsule holes are centered, and the capsule cap is closed with the glue by applying pressure. In the bag-out area, the closed capsule is ejected out of the capsule hole by the bag-out device, and enters the packaging process through the bag-out slide. In the cleaning area, the cleaning device removes contaminants such as drugs and capsule dander from the upper and lower capsule holes. Then, proceed to the next cycle of operation. Since the operation steps in each area take a certain amount of time, the main work disk is intermittently rotated.
The production process of empty capsules is divided into six processes: sol, silicone, drying, stripping, cutting and nesting, and can also be completed by automated production lines. The operating environment has a temperature of 10 to 25 ° C and a relative humidity of 35% to 45%.
When the drug is filled and mass-produced, an automatic filling machine can be used. According to the movement mode of the main working plate, the automatic capsule filling machine can be divided into two types: intermittent rotation and continuous rotation. Although the intermittent rotary phase continuous rotary type differs in the action of the actuator, the process for producing the hard capsule is almost the same. Taking the intermittent rotary automatic capsule filling machine as an example, the structure and working principle of the hard capsule filling machine are introduced.
During operation, the disordered empty capsules dropped from the storage tank are sorted and oriented, and are arranged in a state in which the capsule cap is in the upper state, and fall into the capsule hole on the main working disc one by one. In the capsular area, the capsular device uses vacuum suction to cause the capsule to fall into the hole of the lower capsule, while the capsule cap remains in the upper capsular plate. In the body dislocation area, the upper capsule is removed together with the capsule cap and the upper opening of the capsule is placed below the dosing device. In the filling zone, the metering device fills the drug into the capsule body. In the abandonment zone, the rejecting device removes the unopened empty capsules from the upper capsule hole. In the closed area of ​​the capsule, the axes of the upper and lower capsule holes are centered, and the capsule cap is closed with the glue by applying pressure. In the bag-out area, the closed capsule is ejected out of the capsule hole by the bag-out device, and enters the packaging process through the bag-out slide. In the cleaning area, the cleaning device removes contaminants such as drugs and capsule dander from the upper and lower capsule holes. Then, proceed to the next cycle of operation. Since the operation steps in each area take a certain amount of time, the main work disk is intermittently rotated.
Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells
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