Researchers from the University of Queensland have found that cutting off proteins produced by breast cancer cells can prevent cancer progression.
Dr. Iman Azimi, from the UQ Institute for Pharmacy and Research, said that when breast cancer cells stopped producing proteins called TRPC1, some important pathways in breast cancer progression were discontinued.
Dr. Azimi said: "We identified TRPC1 as a regulator of several pathways that are critical for breast cancer progression when activated by hypoxia.
"With the development of breast cancer, the supply of oxygen will decline, which is called hypoxia.
“This may cause breast cancer to become more aggressive and to resist the currently available treatments.â€
This new study helps identify potential new therapeutic targets for breast cancer progression control.
Dr. Azimi said: "This work is most relevant to women who will develop breast cancer in the future, as these studies may help develop more effective breast cancer treatments to combat existing treatments."
"This study has global significance because it provides researchers with a new understanding of how TRPC1 responds to hypoxia in breast cancer cells and how breast cancer cells metastasize.
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