American University Black Technology: Using microchips to "grow" brain cells on the skin

Release date: 2017-08-10

According to CNET Beijing time on August 9th, it is usually not a good thing to grow something on the skin, but a newly developed technology uses the skin as a "garden" to "grow" according to the needs of the body to treat trauma or disease. Certain types of cells that the body needs, such as cells on the limbs, or even brain cells.

Researchers at the Ohio State University's Wexner Medical Center have developed a nanochip that uses a weak current to transfer new DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) to living skin cells, "reprogramming" skin cells, giving Their new features.


Chandan Sen, director of the Center for Regenerative Medicine and Cell Therapy in Ohio, said in a statement, "The whole process takes only a few seconds, just touch the wound surface and remove it. Cell reprogramming Will start."

According to a paper published in Nature·Nanotechnology, Shen’s team used a technique called “nano-infected tissue” to create new blood vessels in pigs and mice that were seriously injured in the limbs.

They used nanochips to contact the skin of the animal. Within about a week, active blood vessels began to appear and eventually healed the leg wounds of the test animals. This technique is also used to make brain cells from the skin, then "harvest" brain cells and inject them into damaged brains to help them recover.


Shen said, "Using our innovative nanochip technology, injured or damaged organs can be replaced. Our research has proven that the skin is a fertile soil that can grow cells of any declining organs."

Although it sounds like a future, reprogramming skin cells is not a new idea. Five years ago, several studies led to the Nobel Prize in the study of converting skin cells into pluripotent stem cells. However, the new nanochip technology has improved the Nobel Prize-winning study, eliminating the need to convert skin cells into stem cells, directly transforming skin cells into the cell types that the body needs.

Shen said, "Our technology keeps cells under the control of the human immune system, so there is no need for immunosuppression."

Scientists hope to test their technology through human trials in the next step, with the goal of making this technology useful for treating various organ and tissue defects, including Parkinson's syndrome and Alzheimer's disease.

Source: Phoenix Technology

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