Misunderstanding 1 Misconception that antibacterial drugs are antipyretics
Although bacterial infection occurs in diseased animals, fever may be accompanied by the use of antibacterial agents that can cause the inflammation to subside and the body temperature to return to normal. However, not all fevers are caused by bacterial infections. A cold caused by a virus is also a fever. At this time, the use of antibiotics has no effect. When antipyretic analgesics or antiviral drugs are used, the effect is very obvious. The fever caused by protozoa requires the use of antiprotozoal. The drug is effective (such as treatment with erythrocytes with Bernier).
Misunderstanding 2 can not insist on medication according to the course of treatment
Each kind of disease has a certain incubation period, prodromal period, apparent period, and return period, and some farmers want the disease to be treated immediately. If the medicine is used for one day, the curative effect will be seen. If there is no effect, it is considered to be inaccurate. Drugs, repeated use of antibiotics, cured by luck, cure or even lose the best treatment opportunities, resulting in the death of livestock and poultry. There are 46 pigs raised by farmers in the Xiangyang District, Shangqiu City, Henan Province, with an average weight of about 60 kg. On August 17, 2005, 20 pigs suddenly had fever and no food. The farmer invited a local veterinarian for treatment. The veterinarian initially diagnosed the herd as infectious hemolytic streptococcus according to the local epidemic situation and the incidence of the herd, using 30% lincomycin hydrochloride 0.1 ml/kg body weight, 2.5% enrofloxacin. 0.1 ml per kilogram of body weight, 10 ml of each injection of Bupleurum injection. And require the livestock owner to continue medication for 3 to 5 days as a course of treatment. After the livestock owner requested the medication for 1 day, the 20 pigs on the second day did not improve, and the remaining 26 also began to develop, so the livestock owner went to the veterinarian again. Asked if it is suspected that the medication is symptomatic. Will it be a viral flu? After some inquiries by the livestock owner, the veterinarian was afraid that if the treatment effect was not obvious, it would be difficult for the livestock owner to confess, and he would start treatment according to the viral flu. With 10% of 30% metamizol per side, 10ml of ribavirin (No. 560 Bulletin of Ministry of Agriculture has been included in the list of local standard revocation), injection of 15ml of compound Banlangen injection (containing astragalus polysaccharide) .
After using this party, on the morning of August 19th, the pigs began to feed, so the owners used this side for another day. However, on the morning of August 20th, 3 dead pigs were found in the 5 pigsty, and the remaining pigs were more than half. The roots, ankles, abdomen, and hind legs are purple, and their spirits are poor. The appetite is gone. So the owner asked the author to diagnose and treat. After comprehensive inquiry and necropsy, the author dissected a dead pig. The dead pig's throat and trachea were congested. There was a lot of foam. The lungs were congested and swollen. The abdominal cavity had pale yellow effusion and mild fibrinous peritonitis. Pericardial effusion, splenomegaly, the author brought back the disease (liver, spleen) for laboratory examination, smear with Gram staining microscopy, to see single, paired or long-chain cocci and staining was positive, Based on this conclusion, the herd is subacute septic streptococcosis.
Treatment with penicillin 2.4 million units per head, 2 times a day, intravenous injection for 3 to 4 days, ciprofloxacin lactate 5 mg per kilogram body weight intramuscularly, once a day, with this treatment for 4 days, the pigs all improved .
According to the above analysis, the local veterinary diagnosis is correct, but due to his lack of self-confidence, he failed to adhere to the treatment, resulting in the loss of the best time for treatment. If the rescue is not timely, the consequences would be disastrous. Therefore, when treating diseases, it is not always fast, and medication must be maintained during the course of treatment.
Myth 3 Random application of multiple antibiotics for long-term prevention
Such as oxytetracycline, doxycycline, florfenicol, cephalosporins, sulfa drugs and so on. Some medicines are used for a long time, and some medicines are used interchangeably. In fact, such abuse of antibiotics not only has no obvious preventive effect, but will result in long-term use of antibiotics to kill most of the beneficial bacteria causing poultry's digestive tract and respiratory tract immune dysfunction and systemic immune dysfunction. At the same time, most of the drug-resistant strains cause infection by taking advantage of the disease. Once the disease is difficult to treat, there is a large residue of poultry kept in this way.
In a pig farm in Shan County, Shandong Province, 400 pigs were farmed. In mid-July of 2005, due to local epidemic erythropoiesis, toxoplasmosis, and streptococcal disease, livestock owners were afraid that their pigs were infected. The sulfamonomethoxine premix and the florfenicol original powder were purchased from veterinary pharmacies and prevented by the same amount of the mixture. After 20 days of such medication, the overall feed intake of the herds began to decline, and most of the diarrhoea and vomiting occurred. After field veterinary diagnosis of infectious gastroenteritis.
With gentamicin and Viralin (Announcement No. 560 of the Ministry of Agriculture has been included in the list of abolition of local standards), 654-2 treatment for 3 days, diarrhea stopped, and the feed intake remained declining. Most of the pigs had a fever of about 41°C and were depressed. There are red eyelids in the corners of the eyes, rust-colored spots in the pores, pale skin and mucous membranes, difficulty in breathing, and small bleeding points in the ears, the inner side of the thigh, and the lower abdomen. The use of long-acting oxytetracycline, long-acting sulfonamides, florfenicol, and other drugs not only has no effect, but has become more and more serious. Some pigs have died after two days. So I asked for medical treatment, dissection of 2 pigs, organ organs congestion, bleeding, pericardial effusion, splenomegaly and soft, hepatomegaly was yellow-brown, gallbladder filled with gelatin-like bile.
Microscopic examination showed that the parasitic pathogens in the erythrocytes were disc-shaped, globular, and purplish red, about 1.0 micrometer, and one or several parasites within one red blood cell. Due to the long-term use of antibacterial drug ingredients, the destruction of the beneficial bacteria in the digestive tract of pigs leads to digestive disorders, resulting in indigestion, which in turn leads to systemic immune dysfunction, creating resistance to drug-resistant streptococci, Eperythrozoon, etc. The opportunity to cause mixed infections, the author took the following measures:
Antimicrobial cell bodies were treated with yellow pigment intravenously once a day for 3 days; Streptococcus antibiotics used clindamycin combined with lincomycin (intramuscular injection); Increased immune function, with pig immune globulin and Ganoderma lucidum The injections were injected separately and pig electrolysis was added to drinking water to relieve stress. Four days after the comprehensive treatment, the pigs were stable and feed intake gradually returned to normal.
SICHUAN UNIWELL BIOTECHNOLOGY CO.,LTD. , https://www.uniwellbio.com