Clinical study on the treatment of hand, foot and mouth disease in children with traditional Chinese medicine

Clinical study on the treatment of hand, foot and mouth disease in children with traditional Chinese medicine

May 04, 2015 Source: Xinhuanet

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Hand, foot and mouth disease is one of the common infectious diseases in children. It is mainly treated with antiviral drugs for anti-viral drugs and combined with external drugs such as calamine for symptomatic treatment. At the appraisal meeting of the "Basic Antibacterial and Antiviral Basic Research and Clinical Efficacy Observation of Xiaoer Shuangjin Qingre Oral Liquid" held on April 26, Cui Qinghua, a lecturer at the School of Pharmacy of Shandong University of Traditional Chinese Medicine, pointed out in the results report that Pediatric Shuangjin Qingre Oral The liquid has a good inhibitory effect on common bacteria and viruses of respiratory diseases, Coxsackie B3 and EV71.

It is understood that Xiaoer Shuangqingqing Oral Liquid is a classic pediatric Chinese medicine, which can be used to treat fever, cough, sore throat and tonsil enlargement caused by pediatric cold, pediatric pneumonia and acute respiratory infection. Hao Xindong, chairman of Runhua Pharmaceutical, said that Xiaoer Shuangqingqing Oral Liquid is widely used in many provincial and municipal children's hospitals. Because of its good antiviral effect, it can effectively treat hand, foot and mouth disease in children.

Based on the clinical efficacy, Shandong Runhua Pharmaceutical Co., Ltd. and Shandong University of Traditional Chinese Medicine have jointly researched and developed the research project of “Basic Research and Clinical Efficacy Observation of Antibacterial and Antiviral of Xiaoer Shuangqingqing Oral Liquid” after nearly three years of research and development. Cui Qinghua said that the project identified the antibacterial spectrum of Xiaoer Shuangqingqing Oral Liquid. Xiaoer Shuangqingqing Oral Liquid has certain antibacterial activity in vivo and in vitro for various bacteria including Gram-positive bacteria and Gram-negative bacteria. The activity has certain effects on Proteus, Escherichia coli, Staphylococcus aureus, Shigella, and Pseudomonas aeruginosa. The project also clarified the antiviral spectrum of Xiaoer Shuangqingqing Oral Liquid. Xiaoer Shuangqingqing Oral Liquid has anti-RSV virus, H1N1 virus, EV71, COXB3 virus in vitro; animal experiments show that pediatric double gold has anti-in vivo resistance The efficacy of RSV, H1N1 virus.

Cui Qinghua pointed out that after 1660 clinical observations, the results showed that Xiaoer Shuangqingqing Oral Liquid can effectively treat neonatal pneumonia, neonatal jaundice, acute upper respiratory tract infection in children, bronchitis, tonsillitis, herpetic angina, especially The clinical effective rate of treatment of hand, foot and mouth disease is more than 90%. It can effectively improve the clinical symptoms of hand, foot and mouth disease in children, accelerate the disappearance of symptoms, and significantly improve the effect of combined application with western medicine.

It is reported that the research project is a systematic study on the antiviral effect of traditional Chinese medicine in vitro and in vivo. The Shandong Provincial Department of Education organized seven relevant experts to identify the research results. The committee believes that the project is in line with the theory of traditional Chinese medicine and has strong innovation and practicality. It has strong demonstration value for the deep development of proprietary Chinese medicines and the cultivation of large varieties of traditional Chinese medicines, and the research results have reached the international advanced level.

"Chinese medicine has unique characteristics in the treatment of pediatric infectious diseases. The project has a good innovation in the application of traditional Chinese medicine characteristics. The promotion of academic value is of great significance. It is recommended to further deepen the research, increase the Western medical standards for diseases, and at the same time, the indications for medicines. Marketing," said Yao Qingqiang, a researcher at the Shandong Academy of Medical Sciences.

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Natural sweeteners refer to food additives that can sweeten soft drinks. They can be divided into natural sweeteners and synthetic sweeteners according to their sources.

Natural sweeteners are substitutes for sugar. Natural sweeteners considered to be generally safe include stevia, licorice, disodium glycyrrhizinate, tripotassium glycyrrhizinate and trisodium. Natural sweeteners have many uses in the home and in processed foods.

Natural non-nutritive sweeteners are increasingly paid attention to, is the development trend of sweeteners, WHO pointed out that diabetes patients have reached more than 50 million, more than a quarter of the American people require low-calorie food. In sucrose substitutes, the United States mainly uses aspartame, up to more than 90%, Japan mainly uses stevia glycoside, and Europeans are more interested in AK sugar (acesulfames). All three non-nutritive sweeteners are available in China.

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