American professor uses 3D bioprinting to study vascular disease

Release date: 2017-03-01

Guo Hao Dai, a professor of bioengineering at Northeastern University in the United States, is an ambitious and innovative person dedicated to advancing 3D bioprinting to revolutionize modern medical treatment. Specifically, Dai focuses on 3D bioprinting biopsy to explore angiogenesis and further treat vascular disease. Vascular diseases, including diseases such as aneurysms, Raynaud's Syndrome, and lymphedema, are caused by abnormal blood vessels, and millions of people in the United States alone The trouble of such diseases. Associate Professor Dai, from the Department of Bioengineering, hopes to advance the treatment of vascular disease through his specially designed 3D bioprinter.

It is well known that conventional desktop and even industrial 3D printers cannot be used for 3D bioprinting because organic materials are too "fragile" for "rude" machines. 3D bioprinters must be very "exquisite". As Dai explained: "There is a very gentle process to build a living tissue. If we use an industrial 3D printer to print living tissue, the cells simply cannot survive."

To overcome this challenge, Dai developed his own 3D bioprinter and accompanying software to print cultured tissue for human disease modeling and drug discovery. Since his research focuses on vascular and vascular regeneration, researchers have used his machine to make small-channel 3D printed vascular-functional tissues. Although Dai still can't print human tissue in 3D, he believes his current work is industry-leading. "It’s just a step in adding blood flow to the organization," he said.

To date, Dai's 3D bioprinting project has received a lot of support, as it aims to advance stem cell research in the vascular field, and in 2014 won the National Science Foundation CAREER Award and received the National Institutes of Health (NIH) and the American Heart. Association funding. Dai's ultimate goal is to develop an innovative approach to the treatment and exploration of vascular and vascular related diseases.

Source: Bio Valley

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